
Turns Out Your Muscles Are Talking to the Rest of Your Body
By Mark J Kaylor
Turns out your muscles double as a hormone-producing organ.
Every time they contract, they release signaling molecules called myokines into your bloodstream. Researchers have identified hundreds of them, and they travel everywhere: to your liver, fat, bones, immune system, and brain.
Here’s the twist. One of the best-studied, IL-6, usually signals inflammation. But when working muscle releases it, it sets off an anti-inflammatory response instead. Same messenger, opposite message. Another, cathepsin B, makes its way to the brain, where it has been linked to new nerve cell growth and better memory.
That changes what a brisk walk, a set of squats, or carrying groceries up the stairs actually is. Every contraction is a message, and every system you have is listening.
Traditional healing systems have long seen the body as one connected whole. Your muscles have been proving it every time you move.
Reference
1. Skeletal Muscle as a Secretory Organ
Supports: muscle releases hundreds of myokines; muscle-derived IL-6 and its anti-inflammatory effects
Pedersen, B.K., & Febbraio, M.A. (2012). Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nature Reviews Endocrinology, 8(8), 457-465. DOI: 10.1038/nrendo.2012.49

Mark J. Kaylor is a passionate advocate for holistic health and natural remedies, with a focus on extending both lifespan and healthspan. As the founder of the Radiant Health Project and host of Radiant Health Podcast, Mark blends in-depth research with traditional wisdom to empower others on their journey to vibrant health. Through his writing and speaking, he shares insights into the transformative power of herbs, nutrition, and lifestyle practices.
The Radiant Health Project is a not-for-profit initiative dedicated to cutting through wellness industry hype and sharing evidence-informed, traditional wisdom for genuine health.
Disclaimer: All information and results stated here is for educational and entertainment purposes only. The information mentioned here is not specific medical advice for any individual and is not intended to be used for self-diagnosis or treatment. This content should not substitute medical advice from a health professional. Always consult your health practitioner regarding any health or medical conditions.
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